Synthetic Tyrosine tRNA Molecules with Noncanonical Secondary Structures
نویسندگان
چکیده
منابع مشابه
Fundamental of Secondary Structures in Peptide Based Synthetic Nanovaccine Development
The peptides vaccines are composed of the twenty genetically coded amino acids generally exist as an ensemble of different conformational states in solution. The induction of folded conformations in short peptide vaccine sequences may be achieved by the incorporation of stereochemically constrained non-coded amino acids. The aim of this review briefly provides basic understanding of method of v...
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The accumulation of proteins damaged by reactive oxygen species (ROS), conventionally regarded as having pathological potentials, is associated with age-related diseases such as Alzheimer's, atherosclerosis, and cataractogenesis. Exposure of the aromatic amino acid phenylalanine to ROS-generating systems produces multiple isomers of tyrosine: m-tyrosine (m-Tyr), o-tyrosine (o-Tyr), and the stan...
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The discovery of ribozymes led to the proposal of an RNA world, where a single type of molecule was supposedly capable of self-replication and chemical catalysis. We show here that both autocatalysis and organocatalysis can be engineered into a synthetic structure. The compound is shown to selectively accelerate its own formation and catalyze either hydrogenation or nucleophilic addition to alp...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2018
ISSN: 1422-0067
DOI: 10.3390/ijms20010092